Research LibraryPeptide Research

GHK-Cu

Formulation-Specific Classification

A copper-binding peptide studied in topical cosmetic formulations; injectable use is not FDA-approved and lacks rigorous evidence.

Limited human evidenceLast reviewed October 27, 2026

GHK-Cu is a naturally occurring copper-binding peptide complex consisting of the tripeptide glycyl-L-histidyl-L-lysine associated with copper. It has attracted research interest because of its involvement in biological processes associated with skin, extracellular matrix remodeling, and cellular responses to tissue damage. GHK-Cu is commonly discussed in the context of cosmetic skincare and experimental tissue-repair research.

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This page is educational only and is not medical advice. It does not describe an approved treatment for every individual and does not guarantee that any product is available for purchase. Investigational compounds are not offered for sale or treatment booking through this storefront. FDA approval applies to specific drug products and indications, not automatically to every formulation containing the same ingredient.

References & Further Reading

  • 2026 GHK-Cu evidence-mapping review — PubMed / National Library of Medicinesource
  • FDA peptide safety assessment — U.S. Food and Drug Administrationsource
  • FDA cosmetic labeling guidance — U.S. Food and Drug Administration

This entry was last reviewed on October 27, 2026 and requires clinical review before publication. ABF's medical and legal advisers may revise research findings and regulatory information as evidence changes.